MT-BT Asklepion Labs · Research preview

Teaching a CT scan to see what only an MRI could.

MR is the better eye for soft-tissue brain damage — but at 2 a.m. in an emergency room, the scan that's already warm is the CT. MT-BT learns from MR and runs on CT alone.

MR · TEACHERCT · ONLY INPUT
01The idea

MR is the teacher. CT is the only thing the finished system ever has to read.

You'd assume an AI has to see, in the field, the same kind of scan it saw while learning. Ours doesn't.

That asymmetry is the whole bet. The expertise locked inside an MR — and the radiologist who reads it — shouldn't belong only to the hospitals and the hours of day that can afford both. If a routine CT can be taught to carry some of that signal forward, the gap between the best-equipped hospital and the one down the road gets a little narrower.

CT-onlyat inference — no MR at the point of care
0.92median MR→CT brain alignment (Dice)
Patient-leveltrain/test split — never by scan
02Method

Teach with one scan, run on another.

For a single patient, an MR and a CT are two photographs of the same brain from slightly different cameras. Line them up precisely and anything an expert marks on the MR can be carried onto the CT — pixel for pixel, in the same place.

01 · ALIGN

Register MR to CT

The two scans are brought into a shared coordinate space — correcting first for rotation and position, then scale, then the subtle local stretching two scanners of the same head always disagree on.

02 · TRANSFER

Carry the label across

The injured region is marked on the MR, where damage is most visible, then projected onto the aligned CT. The CT inherits an expert-grade label it could never have produced on its own.

03 · LEARN

Predict from CT alone

Across enough CT-plus-inherited-label pairs, a segmentation model learns the pattern directly on CT. From then on, it works from a CT and nothing else.

The label is only as good as the alignment underneath it, so we throw work away on purpose. Every transferred outline is checked — does it sit inside the brain, respect the midline, follow the tissue boundaries it should? A poorly aligned case is cut rather than given a second chance to mislead the model. Improving the data beats improving the model more often than anyone expects.
03Live case

See it on a real case.

Scrub through the slices of a representative patient. Switch the base image between CT and diffusion MR, and toggle the two overlays — the clinician label transferred from MR, and the model's prediction made from CT alone. The Dice score is their overlap on the current slice.

Loading representative case…
04A second opinion

Two models, reported together.

Taught what damage looks like

The supervised reader

Trained on transferred MR labels, it flags the kind of injury experts have marked before — the model behind the live case above.

Has only seen healthy brains

The anomaly spotter

A different system studies normal anatomy until it can reconstruct a healthy brain from memory. Hand it a real scan; wherever reconstruction and reality disagree, you get a map of unfamiliarity. It works the way you spot a stranger in a family photo — you don't need to know who they are to know they don't belong.

Where the two agree, confidence is higher. Where they disagree, that's not a failure — it's exactly the kind of uncertainty a clinician should have surfaced to them rather than hidden.
05What we're careful about

Easy to make a brain model look brilliant. Harder to make it honest.

NO LEAKAGE

Split by patient, never by scan

The most common way these systems lie to their creators is data leakage — slices of the same patient landing in both training and testing, so the model is graded on faces it has memorised. We split strictly by patient. The numbers we earn that way are smaller and real.

HUMAN IN THE LOOP

A person at every step that matters

Labels are produced or reviewed by specialists, and transferred outlines are checked before they ever reach the model. The system highlights regions for a qualified clinician — it does not decide.

READ THE FAILURES

Sort every miss by why

Weak alignment, a too-small lesion, scanner artefact, low contrast. That catalogue — not the average score — is what tells us which part of the pipeline to fix next.

CALIBRATED OUTPUT

Confidence you can question

The output is a damage-likelihood map with reviewable confidence, designed to be interrogated by the person reading the image — not a verdict handed down.

06Build with the Labs

A bet about access.

MT-BT is a wedge into a larger thesis: the best medical signal is often locked in data hospitals already have. We partner with investors, hospitals, and clinical teams who want to widen who that signal reaches. If that's you, let's talk.

What this is, and what it isn't. MT-BT is research. It is designed to highlight regions of a scan for a qualified clinician to review — not to diagnose, decide, or replace the person reading the image. It is not a medical device and is not intended for diagnostic use.